Enzyme-Substrate Pair Prediction

This prediction model is not the original ESP model, but uses our new ProSmith model, which results in improved prediction accuracy.

If you use ESP, please cite: Kroll et al. (2024). A multimodal Transformer Network for protein-small molecule interactions enhances predictions of kinase inhibition and enzyme-substrate relationships. PLOS Computational Biology. doi:10.1371/journal.pcbi.1012100